Isaiah Prince provided solid pass-protection and kept the edge clean, contributing to the 49ers’ depth at tackle. His 63.8 pass-pro and 71.5 run-block grades indicate steady, if unspectacular, work that could earn him regular-season reps behind the starters as SF navigates suspensions and injuries.

Isaiah Prince sustained a knee injury at left tackle. The backup situation behind him will determine early-season pass protection and team stability, potentially influencing QB safety and SF’s offensive line depth in the opening weeks.

Isaiah Prince is a veteran swing tackle for San Francisco whose left-leg injury during the preseason finale raises depth concerns at tackle. His status will influence who steps in at left/right tackle—likely Spencer Burford, Austen Pleasants, or Nick Zakelj—and could affect SF’s early-season run and pass protection schemes.